SCAN_Divergence

we selected nine representative neural lineage master regulators (i.e., FOXG1, LHX2, NEUROD1, NEUROG1, OLIG2, PAX6, REST, SOX2, TBR1) and downloaded the amino acid sequences of homologous counterparts for a total of 142 species. Then, we performed pairwise comparisons with Homo sapiens to investigate the molecular divergence of crucial neural regulators during animal evolution. The comparison results were stored in the SCAN_Divergence module which can be accessed via a hierarchical selection of classification, species and data set. Alternatively, users can browse the picture and name of the species below to choose any species they are interested in for further inspection.